| Local | Visita | Hora | |
|---|---|---|---|
| Lunes 09 de Octubre | |||
| Elche | 2 - 1 | FC Andorra | 12:00 |
| Villarreal II | 3 - 1 | Espanyol | 14:00 |
| Sportivo Ameliano | 0 - 2 | Sportivo Luqueno | 17:30 |
| Toluca W | 2 - 4 | Guadalajara W | 18:00 |
| Pumas UNAM W | 6 - 0 | Necaxa W | 20:00 |
| Monterrey W | 3 - 1 | Querétaro W | 22:00 |
| Libertad | 1 - 0 | Guayaquil City FC | 19:00 |
| Barracas Central | 2 - 1 | Colon Santa Fe | 16:00 |
| Arsenal Sarandi | 0 - 0 | Banfield | 16:00 |
| Velez Sarsfield | 3 - 1 | Atletico Tucuman | 18:30 |
