| Local | Visita | Hora | |
|---|---|---|---|
| Martes 26 de Septiembre | |||
| Preussen Munster | 0 - 4 | Bayern Munich | 13:45 |
| Salford City | 0 - 4 | Burnley | 13:45 |
| Exeter City | 1 - 0 | Luton | 13:45 |
| Ipswich | 3 - 2 | Wolves | 13:45 |
| Manchester United | 3 - 0 | Crystal Palace | 14:00 |
| AVS | 1 - 2 | Arouca | 14:15 |
| Juventus | 1 - 0 | Lecce | 13:45 |
| Lille | 1 - 2 | Reims | 14:00 |
| Nuova Cosenza | 1 - 2 | Cremonese | 11:15 |
| Sevilla | 5 - 1 | Almeria | 12:00 |
| Zofingen | 2 - 0 | Emmen | 13:00 |
| Spezia | 0 - 0 | Brescia | 13:30 |
| Venezia | 1 - 3 | Palermo | 13:30 |
| Mallorca | 2 - 2 | Barcelona | 14:30 |
| Amiens | 0 - 0 | Ajaccio | 13:45 |
| Rodez | 2 - 1 | Estac Troyes | 13:45 |
| Quevilly | 0 - 1 | Angers | 13:45 |
| Guingamp | 0 - 0 | Bordeaux | 13:45 |
| Auxerre | 4 - 0 | Annecy | 13:45 |
| Corinthians | 1 - 1 | Fortaleza EC | 19:30 |
| CA La Paz | 1 - 0 | Tlaxcala | 20:05 |
| Cimarrones | 3 - 2 | Monarcas | 22:05 |
| Guadalajara Chivas | 1 - 3 | Mazatlán | 20:05 |
| Imbabura | 0 - 3 | UT Cotopaxi | 19:00 |
| Union Magdalena | 3 - 4 | Deportivo Cali | 18:15 |
| Alianza Petrolera | 2 - 1 | Once Caldas | 18:25 |
| Deportivo Pasto | 1 - 0 | Huila | 20:30 |
