| Local | Visita | Hora | |
|---|---|---|---|
| Lunes 10 de Abril | |||
| Deportes Rengo | 1 - 0 | Curico Unido | 16:00 |
| Trasandino | 1 - 1 | Union La Calera | 18:00 |
| Barcelona SC | 4 - 1 | Cumbayá | 19:00 |
| Liverpool | 3 - 1 | Plaza Colonia | 13:30 |
| La Luz | 2 - 1 | Boston River | 18:15 |
| Academia Cantolao | 1 - 2 | Union Comercio | 15:30 |
| Sportivo Ameliano | 2 - 5 | Libertad | 17:00 |
| Cesar Vallejo | 3 - 0 | Deportivo Garcilaso | 18:00 |
| Club Guarani | 3 - 1 | General Caballero | 19:30 |
| Atletico Nacional | 0 - 1 | Junior | 18:00 |
| Alianza Petrolera | 3 - 1 | Santa Fe | 18:20 |
| Deportes Tolima | 3 - 1 | Deportivo Pasto | 20:05 |
| San Telmo | 1 - 2 | Guillermo Brown | 13:30 |
| Nueva Chicago | 1 - 0 | Flandria | 15:00 |
| Defensores De Belgrano | 2 - 0 | Patronato | 17:05 |
| Estudiantes de Rio Cuarto | 1 - 1 | Gimnasia M. | 19:00 |
| Temperley | 1 - 0 | Defensores Unidos | 19:10 |
| Gil Vicente | 0 - 0 | Chaves | 14:15 |
| Barcelona | 0 - 0 | Girona | 14:00 |
| Benevento | 1 - 3 | Spal | 05:30 |
| Reggina | 1 - 0 | Venezia | 08:00 |
| Frosinone | 2 - 0 | Ascoli | 08:00 |
| como | 2 - 2 | Genoa | 08:00 |
| Cittadella | 0 - 1 | Parma | 08:00 |
| Pisa | 0 - 0 | Cagliari | 11:00 |
| Alaves | 0 - 0 | FC Andorra | 14:00 |
| West Brom | 2 - 2 | QPR | 09:00 |
| Norwich | 0 - 0 | Rotherham | 09:00 |
| Luton | 3 - 1 | Blackpool | 09:00 |
| Coventry | 2 - 2 | Watford | 09:00 |
| Burnley | 2 - 0 | Sheffield Utd | 14:00 |
