| Local | Visita | Hora | |
|---|---|---|---|
| Viernes 10 de Marzo | |||
| Vancouver Whitecaps | 1 - 1 | FC Dallas | 16:00 |
| La Luz | 0 - 3 | Cerro Largo | 16:30 |
| Barracas Central | 1 - 1 | Independiente | 14:00 |
| Instituto Cordoba | 1 - 1 | Atletico Tucuman | 18:00 |
| Argentinos JRS | 1 - 1 | Arsenal Sarandi | 18:00 |
| ADT | 1 - 0 | Sport Boys | 14:30 |
| Deportes Copiapo | 0 - 0 | Union La Calera | 17:30 |
| Jaguares | 1 - 2 | Huila | 18:40 |
| Atletico DE Rafaela | 1 - 2 | Ferro Carril Oeste | 18:00 |
| Moreirense | 3 - 1 | Penafiel | 12:00 |
| FC Koln | 0 - 2 | VfL BOCHUM | 13:30 |
| FC Porto | 3 - 2 | Estoril | 14:15 |
| Cadiz | 2 - 2 | Getafe | 14:00 |
| Spezia | 2 - 1 | Inter | 13:45 |
| Lille | 3 - 3 | Lyon | 14:00 |
| Dordrecht | 0 - 4 | De Graafschap | 13:00 |
| Willem II | 2 - 3 | PEC Zwolle | 13:00 |
| VVV Venlo | 4 - 0 | Den Bosch | 13:00 |
| Roda | 1 - 2 | Telstar | 13:00 |
| FC OSS | 2 - 3 | ADO Den Haag | 13:00 |
| NAC Breda | 4 - 1 | MVV | 13:00 |
| Heracles | POSP | Jong AZ | 13:00 |
| FC Eindhoven | 5 - 1 | Jong Ajax | 13:00 |
| Cagliari | 4 - 1 | Ascoli | 13:30 |
| Querétaro W | 0 - 1 | Guadalajara W | 17:05 |
| Tijuana W | 2 - 0 | Tigres UANL W | 19:06 |
| Atletico San Luis | 2 - 0 | Club Queretaro | 19:05 |
| Puebla | 1 - 0 | Guadalajara Chivas | 21:05 |
