| Local | Visita | Hora | |
|---|---|---|---|
| Lunes 06 de Marzo | |||
| Potencia | 1 - 1 | Rentistas | 14:00 |
| Cumbayá | 1 - 0 | Independiente del Valle | 18:00 |
| Plaza Colonia | 3 - 1 | Fenix | 16:30 |
| Arsenal Sarandi | 0 - 1 | Belgrano | 14:00 |
| Godoy Cruz | 2 - 0 | Racing Club | 14:00 |
| Boca Juniors | 0 - 0 | Defensa Y Justicia | 18:00 |
| Deportivo Municipal | 0 - 3 | Deportivo Garcilaso | 14:00 |
| Cusco | 2 - 1 | Union Comercio | 14:30 |
| Huila | 3 - 2 | Chico | 19:00 |
| Defensores De Belgrano | 4 - 1 | Guillermo Brown | 14:00 |
| Patronato | 6 - 0 | Alvarado | 15:00 |
| Casa Pia | 2 - 1 | Paços de Ferreira | 14:15 |
| Osasuna | 0 - 0 | Celta Vigo | 14:00 |
| Sassuolo | 3 - 2 | Cremonese | 11:30 |
| Torino | 1 - 0 | Bologna | 13:45 |
| Brentford | 3 - 2 | Fulham | 14:00 |
| Jong Utrecht | 1 - 3 | Roda | 13:00 |
| Jong PSV | 1 - 2 | NAC Breda | 13:00 |
| Jong AZ | 2 - 2 | Willem II | 13:00 |
| De Graafschap | 2 - 0 | Helmond Sport | 13:00 |
| ADO Den Haag | 0 - 3 | Heracles | 13:00 |
| Genoa | 4 - 0 | Nuova Cosenza | 13:30 |
| Toluca W | 0 - 0 | Pumas UNAM W | 17:00 |
| Pachuca W | 2 - 3 | América W | 19:05 |
| Santos Laguna W | 3 - 0 | Necaxa W | 21:10 |
| Villarreal II | 1 - 0 | Alaves | 14:00 |
