| Local | Visita | Hora | |
|---|---|---|---|
| Lunes 16 de Mayo | |||
| Ituano | 1 - 1 | Gremio | 18:00 |
| Boston River | 2 - 3 | Liverpool | 16:00 |
| Gualaceo SC | 2 - 1 | Guayaquil City FC | 19:00 |
| Curico Unido | 4 - 1 | A. Italiano | 19:30 |
| Carlos Stein | 1 - 1 | Atletico Grau | 11:00 |
| Nueva Chicago | 1 - 0 | Atlanta | 13:00 |
| Ferro Carril Oeste | 1 - 0 | Guillermo Brown | 17:00 |
| Gimnasia Jujuy | 1 - 0 | Belgrano | 17:10 |
| Almirante Brown | 2 - 2 | Villa Dalmine | 19:10 |
| Club Guarani | 3 - 0 | 12 de Octubre | 19:00 |
| Sampdoria | 4 - 1 | Fiorentina | 11:30 |
| Juventus | 2 - 2 | Lazio | 13:45 |
| Newcastle | 2 - 0 | Arsenal | 14:00 |
| Guadalajara W | 2 - 0 | Tigres UANL W | 19:05 |
| Monterrey W | 2 - 1 | Pachuca W | 21:05 |
| Huddersfield | 1 - 0 | Luton | 13:45 |
