| Local | Visita | Hora | |
|---|---|---|---|
| Jueves 02 de Diciembre | |||
| AZ Alkmaar | 2 - 1 | Fortuna Sittard | 11:45 |
| Guijuelo | 1 - 1 | Rayo Vallecano | 12:00 |
| San Agustín | 0 - 4 | Osasuna | 12:00 |
| Huracán Melilla | 0 - 8 | Levante | 12:00 |
| Gernika | 1 - 2 | Eibar | 12:00 |
| Utrillas | 0 - 3 | Valencia | 12:30 |
| Leioa | 0 - 2 | Elche | 13:00 |
| Xerez Deportivo | 1 - 2 | Leganes | 13:45 |
| Villa de Fortuna | 0 - 7 | Cadiz | 14:00 |
| Casa Pia | 1 - 0 | Varzim | 14:15 |
| Tottenham | 2 - 0 | Brentford | 13:30 |
| Manchester United | 3 - 2 | Arsenal | 14:15 |
| Torino | 2 - 2 | Empoli | 11:30 |
| Lazio | 4 - 4 | Udinese | 13:45 |
| Ajax | 5 - 0 | Willem II | 14:00 |
| Venados FC | 0 - 2 | Atlante FC | 19:00 |
| U.N.A.M. - Pumas | 0 - 1 | Atlas | 21:00 |
| Bahia | 2 - 3 | Atletico-MG | 15:00 |
| Gremio | 3 - 0 | Sao Paulo | 17:00 |
| Deportes Tolima | 2 - 0 | America de Cali | 17:00 |
| Millonarios | 3 - 0 | Alianza Petrolera | 19:05 |
